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Indefinite passive immunization after liver transplantation for hepatitis B

✍ Scribed by Timothy Pruett


Book ID
111723278
Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
43 KB
Volume
8
Category
Article
ISSN
1527-6465

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Patients who undergo transplantation for hepatitis B virus (HBV)-related diseases are treated indefinitely with hepatitis B hyperimmunoglobulin (HBIG) to prevent endogenous HBV reinfection of the graft. Active immunization with standard hepatitis B vaccines in these patients has recently been report

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Cellular immunity plays an important role in the long-term control of hepatitis B virus (HBV) infection. We studied the changes in HBV-specific CD4 T cell immunity after orthotopic liver transplantation (OLT) for chronic hepatitis B under antiviral prophylaxis. T cell proliferation and interferon-β₯