Lamivudine after hepatitis B immune globulin is effective in preventing hepatitis B recurrence after liver transplantation
โ Scribed by S. Forrest Dodson; Michael E. de Vera; C. Andrew Bonham; David A. Geller; Jorge Rakela; John J. Fung
- Book ID
- 111722907
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 57 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1527-6465
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Immunoprophylaxis using intravenous (IV) hepatitis B immune globulin (HBIG) decreases the recurrence of hepatitis B virus (HBV) infection after orthotopic liver transplantation (OLT). However, IV HBIG is expensive, has significant side effects, and is inconvenient to administer. An alternative appro
Patients undergoing liver transplantation for hepatitis B-related liver disease are prone to recurrence. The mainstay of prophylaxis has been passive immunotherapy with hepatitis B immune globulin (HBIG). Antiviral therapy with lamivudine has proven effective in lowering hepatitis B virus (HBV) DNA