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Increasing the solubility of phenazepam by forming solid dispersions

✍ Scribed by I. I. Krasnyuk; O. V. Manakhova; R. U. Khabriev; V. A. Popkov; V. Yu. Reshetnyak; O. I. Krasnyuk


Publisher
Springer
Year
2010
Tongue
English
Weight
135 KB
Volume
44
Category
Article
ISSN
0091-150X

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The present study investigates the release mechanism of benznidazole (BNZ) in solid dispersions with polyethylene glycol 6000 (PEG 6000) and polyvinylpirrolydone K-30 (PVP K-30), with a view to observing the increase in solubility of BNZ in water in the presence of these two hydrophilic polymers. Th