Increases in the solubility of Mezapam by forming solid dispersions
β Scribed by I. I. Krasnyuk; A. S. Lapshova; R. U. Khabriev; V. A. Popkov; V. Yu. Reshetnyak; S. O. Zvereva; O. I. Krasnyuk
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 211 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0091-150X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The present study investigates the release mechanism of benznidazole (BNZ) in solid dispersions with polyethylene glycol 6000 (PEG 6000) and polyvinylpirrolydone K-30 (PVP K-30), with a view to observing the increase in solubility of BNZ in water in the presence of these two hydrophilic polymers. Th
General expressions are derived for the solubility of hydrogen in equilibrium with internal11 and externally stressed hydrides. These expressions are applied to some data for the terminal solid solubility (TSS) of hydrogen in zirconium and its alloys to estimate (a) the amount of hydride-matrix misf
The solubility of E2050, supplied as a dihydrochloride salt, in aqueous solutions at different pHs was studied. Two pK(a)s controlling the equilibrium between the various protonated species were determined. The solubility-pH profile of E2050 is expected to be high in acidic solutions because protona