✦ LIBER ✦

Increasing incidence of breast cancer in family with BRCA1 mutation

✍ Scribed by NAROD, S

Book ID: 123379105
Publisher: The Lancet
Year: 1993
Tongue: English
Weight: 330 KB
Volume: 341
Category: Article
ISSN: 0140-6736
DOI: 10.1016/0140-6736(93)92468-9

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

BRCA1 mutations in German breast-cancer

BRCA1 mutations in German breast-cancer families

✍ Burkhard Jandrig; Klaus Grade; Susanne Seitz; Beate Waindzoch; Manuela Müller; E 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 French ⚖ 488 KB 👁 2 views

We analyzed germline mutations of the BRCAl gene in 20 German breast/ovarian-cancer families. BRCA I mutations cosegregating with breast-cancer susceptibility were identified in 3 of these families. All mutations were found to generate a premature stop codon leading to the synthesis of truncated BRC

Low incidence of BRCA1 mutations among I

Low incidence of BRCA1 mutations among Italian families with breast and ovarian cancer

✍ Manuela Santarosa; Alessandra Viel; Riccardo Dolcetti; Diana Crivellari; Maria D 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 French ⚖ 139 KB 👁 2 views

Most familial breast or ovarian cancers are thought to be due to highly penetrant mutations in the predisposing genes BRCA1 and BRCA2. The cloning of these genes has opened a new era for the genetic counseling of women with a family history of breast or ovarian cancer. To estimate the incidence of d

BRCA1 gene mutations in Chinese families

BRCA1 gene mutations in Chinese families with breast cancer

✍ Shi, Yurong ;Li, Chenbin ;Niu, Ruifang ;Hao, Xishan ;Zhi, Xiangcheng ;Ning, Lian 📂 Article 📅 2005 🏛 Springer-Verlag ⚖ 714 KB

BRCA1 and BRCA2 mutations in Russian fam

BRCA1 and BRCA2 mutations in Russian familial breast cancer

✍ Irina V. Tereschenko; Victoria M. Basham; Bruce A.J. Ponder; Paul D.P. Pharoah 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 24 KB 👁 2 views

We have screened index cases from 25 Russian breast/ovarian cancer families for germ-line mutations in all coding exons of the BRCA1 and BRCA2 genes, using multiplex heteroduplex analysis. In addition we tested 22 patients with breast cancer diagnosed before age 40 without family history and 6 patie

Incidence of BRCA1 and BRCA2 mutations i

Incidence of BRCA1 and BRCA2 mutations in 54 Chilean families with breast/ovarian cancer, genotype–phenotype correlations

✍ Marcela Gallardo; Antonia Silva; Lorena Rubio; Carolina Alvarez; Carolina Torrea 📂 Article 📅 2005 🏛 Springer US 🌐 English ⚖ 180 KB

BRCA1 2080insA mutation in familial brea

BRCA1 2080insA mutation in familial breast cancer

✍ Aliya S. Alansari; Mansour Al-Moundhri; Marium M. Al-Nabhani; Shoaib A. Al-Zidja 📂 Article 📅 2008 🏛 Springer US 🌐 English ⚖ 143 KB