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Increasing complexity of Ras signaling

โœ Scribed by Campbell, Sharon L; Khosravi-Far, Roya; Rossman, Kent L; Clark, Geoffrey J; Der, Channing J

Book ID
110061647
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
575 KB
Volume
17
Category
Article
ISSN
0950-9232

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## Abstract Activating __ras__ mutations are frequently found in malignant tumors of the pancreas, colon, lung and other tissues. RAS activates a number of downstream pathways that ultimately cause cellular transformation. Several recent studies suggested that one of those pathways involves Aurora