## Abstract The __in vivo__ disposition and antitumor efficacy of a newly developed phosphinic matrix metalloproteinase inhibitor (RXP03) were examined. RXP03 potently inhibits MMPβ11, MMPβ8 and MMPβ13, but not MMPβ1 and MMPβ7. Twentyβfour hours after i.p. injection into mice, most of the RXP03 was
β¦ LIBER β¦
Antitumor Efficacy of Hypothemycin, A New Ras-signaling Inhibitor
β Scribed by Tanaka, Hidekazu ;Nishida, Kazuyo ;Sugita, Kenji ;Yoshioka, Takayuki
- Book ID
- 108581690
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 1999
- Tongue
- English
- Weight
- 243 KB
- Volume
- 90
- Category
- Article
- ISSN
- 0910-5050
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Dosing and scheduling influence the anti
β
Vincent Dive; Kumari L. Andarawewa; Anne Boulay; Magdalini Matziari; Fabrice Bea
π
Article
π
2004
π
John Wiley and Sons
π
French
β 290 KB
Dual antitumor mechanisms of Notch signa
β
Shigeo Masuda; Keiki Kumano; Takahiro Suzuki; Taisuke Tomita; Takeshi Iwatsubo;
π
Article
π
2009
π
John Wiley and Sons
π
English
β 597 KB
Design and Characterization of a New Cla
β
SONIA COLOMBO; FRANCESCO PERI; RENATA TISI; FRANCESCO NICOTRA; ENZO MARTEGANI
π
Article
π
2004
π
John Wiley and Sons
π
English
β 70 KB
Efficacy and safety of spirapril, a new
β
I. Kantola; A. TerΓ©nt; T. Honkanen; V. JΓ€rvelΓ€inen; K. Ekman; M. Kataja
π
Article
π
1996
π
Springer
π
English
β 241 KB
A phase II study of the Ras-MAPK signali
β
Warren P. Mason; Karl Belanger; Garth Nicholas; Isabelle Vallières; David Mathie
π
Article
π
2011
π
Springer US
π
English
β 310 KB
Antitumor effect of a new selective matr
β
A. Matsushita; M. Onda; E. Uchida; R. Maekawa; T. Yoshioka
π
Article
π
2001
π
John Wiley and Sons
π
French
β 402 KB
The antitumor effect of a new matrix metalloproteinase inhibitor, MMI-166, which is a selective inhibitor of MMP-2 and -9, was examined in the hamster pancreatic cancer cell line PGHAM-1. In vitro, MMI-166 inhibited the gelatinase activity of MMP-2 and -9 derived from PGHAM-1 cells, and dose-depende