IncreasedMUTYHmutation frequency among Dutch families with breast cancer and colorectal cancer
β Scribed by Marijke Wasielewski; Astrid A. Out; Joyce Vermeulen; Maartje Nielsen; Ans van den Ouweland; Carli M. J. Tops; Juul T. Wijnen; Hans F. A. Vasen; Marjan M. Weiss; Jan G. M. Klijn; Peter Devilee; Frederik J. Hes; Mieke Schutte
- Publisher
- Springer US
- Year
- 2010
- Tongue
- English
- Weight
- 225 KB
- Volume
- 124
- Category
- Article
- ISSN
- 0167-6806
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The risk of colorectal cancer was examined among spouses of approximately 10,000 colorectal cancer patients. A total of 8,095 spouses were identified, and cancer cases in this cohort were sought in the Danish Cancer Registry. No excess risk was found for colorectal cancer as such. The data were also
## Abstract To investigate the genetic factor in the development of colorectal cancer, a cohort study was undertaken of parents of patients with this disease. All 1,524 patients, who were diagnosed with colorectal cancer in Denmark in 1982β84 and were below the age of 60 years, were selected from t