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Increased type-IV collagenase (MMP-2 and MMP-9) activity following preoperative radiotherapy in rectal cancer

โœ Scribed by Kumar, A; Collins, H M; Scholefield, J H; Watson, S A


Book ID
111724172
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
316 KB
Volume
82
Category
Article
ISSN
0007-0920

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We have identified a novel membrane-type matrix metalloproteinase (MT-MMP) expressed on the cell surface and inducing activation of pro-gelatinase A in vitro. In this study, we further examined the possibility that MT-MMP is the activator of pro-gelatinase A in tumors as well as in vitro. Expression