Activity of type IV collagenases (MMP-2 and MMP-9) in primary pulmonary carcinomas: a quantitative analysis
โ Scribed by E. Hrabec; M. Strek; D. Nowak; J. Greger; M. Suwalski; Z. Hrabec
- Book ID
- 106123147
- Publisher
- Springer-Verlag
- Year
- 2002
- Tongue
- English
- Weight
- 192 KB
- Volume
- 128
- Category
- Article
- ISSN
- 1432-1335
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Enhanced expression of the type IV collagenases MMP-2 and MMP-9, or lack of their inhibitors TIMP-1 and TIMP-2, has been associated with tumour invasion and metastatic potential in several experimental models. Regulation of enzyme activity is clearly a key step in tumour invasion, and recently a pot
We have identified a novel membrane-type matrix metalloproteinase (MT-MMP) expressed on the cell surface and inducing activation of pro-gelatinase A in vitro. In this study, we further examined the possibility that MT-MMP is the activator of pro-gelatinase A in tumors as well as in vitro. Expression