Increased TGFβ Type II Receptor Expression Suppresses the Malignant Phenotype and Induces Differentiation of Human Neuroblastoma Cells
✍ Scribed by Alessandra Turco; Susanna Scarpa; Anna Coppa; Gianluca Baccheschi; Camilla Palumbo; Carlo Leonetti; Gabriella Zupi; Giulia Colletta
- Book ID
- 115603552
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 427 KB
- Volume
- 255
- Category
- Article
- ISSN
- 0014-4827
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## Abstract We examined the effect of stable transfection of dominant negative TβR‐II (dn TβR‐II) cDNA in a human oral carcinoma cell line that contained normal __Ras__ and was growth inhibited by TGF‐β1. Two clonal cell lines containing dn TβR‐II were isolated and compared to the vector‐only contr