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Increased susceptibility to hepatocarcinogenicity of Nrf2-deficient mice exposed to 2-amino-3-methylimidazo[4,5-f]quinoline

✍ Scribed by Yasuki Kitamura; Takashi Umemura; Keita Kanki; Yukio Kodama; Sachiko Kitamoto; Koichi Saito; Ken Itoh; Masayuki Yamamoto; Toshiaki Masegi; Akiyoshi Nishikawa; Masao Hirose


Book ID
108583779
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
136 KB
Volume
98
Category
Article
ISSN
1347-9032

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In vivo mutational analysis of liver DNA
✍ Keita Kanki; Akiyoshi Nishikawa; Ken-ichi Masumura; Takashi Umemura; Takayoshi I πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 222 KB πŸ‘ 1 views

## Abstract In order to cast light on carcinogen‐specific molecular mechanisms underlying experimental hepatocarcinogenesis in rats, in vivo mutagenicity and mutation spectra of known genotoxic rat hepatocarcinogens __N__‐nitrosopyrrolidine (NPYR), and 2‐amino‐3‐methylimidazo[4,5‐__f__]quinoline (I