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Increased risk of noncardia gastric cancer associated with proinflammatory cytokine gene polymorphisms

✍ Scribed by Emad M El-Omar; Charles S Rabkin; Marilie D Gammon; Thomas L Vaughan; Harvey A Risch; Janet B Schoenberg; Janet L Stanford; Susan T Mayne; James Goedert; William J Blot; Joseph F Fraumeni Jr; Wong-ho Chow

Book ID
119426426
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
116 KB
Volume
124
Category
Article
ISSN
0016-5085

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## Abstract __Helicobacter pylori cag__A‐positive strains and host cytokine proinflammatory polymorphisms have been associated with gastric carcinoma. However, the individual role of each factor has not been evaluated yet. Our aim was to evaluate whether IL‐1 gene cluster and tumor necrosis factor‐