## Abstract ## Background. Head and neck squamous cell carcinoma (HNSCC) continues to cause significant morbidity and mortality. Overexpression of specific phase II gene products may represent an important biomarker. One regulator of phase II gene expression is the transcription factor nuclear fac
Increased proteasome subunit protein expression and proteasome activity in colon cancer relate to an enhanced activation of nuclear factor E2-related factor 2 (Nrf2)
✍ Scribed by Arlt, A; Bauer, I; Schafmayer, C; Tepel, J; Müerköster, S Sebens; Brosch, M; Röder, C; Kalthoff, H; Hampe, J; Moyer, M P
- Book ID
- 109971067
- Publisher
- Nature Publishing Group
- Year
- 2009
- Tongue
- English
- Weight
- 785 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0950-9232
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Adenosine, a purine nucleoside, has been reported to suppress the inflammatory responses of microglia in the brain. However, the underlying mechanisms of its anti‐inflammatory action are unclear at present. Here we show that adenosine reduces the increase in intracellular reactive oxyge
## Abstract Chemicals that activate nuclear factor‐E2‐related factor 2 (Nrf2) often increase multidrug‐resistance‐associated protein (Mrp) expression in liver. Hepatocyte‐specific deletion of Kelch‐like ECH‐associated protein 1 (__Keap1__) activates Nrf2. Use of hepatocyte‐specific __Keap1__ deleti