Increased mutagenic effect of ethyl methanesulfonate when dissolved in dimethyl sulfoxide
β Scribed by C.R. Bhatia
- Book ID
- 118952229
- Publisher
- Elsevier Science
- Year
- 1967
- Tongue
- English
- Weight
- 132 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0027-5107
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π SIMILAR VOLUMES
Recent insights (1) in the remarkable solvent properties of dimethyl eulfoxida (DMSO), and our own interest in the chemistry of isopropcnyl ethers (2) led u8 to consider the poraibility of direot 0-alkylation of ethyl aoetoaoetate in that solvent. The connection i# that Kornblum'rr work (3) suggests
In our last pa&u (I) it ras reported that in the olkaline'hydrolysis of substituted ethyl bensoates the change of the solvent from' 85 %(rt.) aqueous ethanol to 3 %(rt.) aqueous ethanol caused 5C times increase in the rate of the unsubstituted compound and decrease to a half in the Bammett p value,
A 1% (v/v) solution ofdimethyl sulfoxide (DMSO) added to the saline bath of isolated Balanus eburneus photoreceptors increased receptor potential amplitude by 40-50% and shortened time to peak amplitude and latency by 20-25%. The light-sensitive membrane current of voltage-clamped cells was increase