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Increased mRNA expression of phospholipase D (PLD) isozymes during granulocytic differentiation of HL60 cells

✍ Scribed by Shigeru Nakashima; Kenji Ohguchi; Michael A Frohman; Yoshinori Nozawa

Book ID
117049624
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
276 KB
Volume
1389
Category
Article
ISSN
0005-2760

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## Abstract During differentiation of human leukemic HL60 cells into granulocytes, sustained increases in intracellular pH and Na^+^/H^+^ antiporter activity have been observed. In the present study we report that retinoic acid (RA)‐induced granulocytic differentiation of HL60 cells causes an ∼18‐f