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Increased levels of urinary leukotriene E4 in children with severe atopic eczema/dermatitis syndrome

✍ Scribed by K. Øymar; L. Aksnes


Book ID
110885524
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
93 KB
Volume
60
Category
Article
ISSN
0105-4538

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Leukotriene synthesis may be increased in a variety of inflammatory diseases. Urinary leukotriene E4 is a stable metabolite of leukotrienes C4 and D4 which has previously been found to be increased in exacerbations of severe asthma and after antigen inhalation. Levels of urinary LTE4 in seven patien

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## Background: Synthesis of cysteinyl leukotrienes (lts) is known to play a part in the pathogenesis of inflammatory diseases. ## Objectives: To define the involvement of cysteinyl lts in atopic dermatitis (ad). ## Methods: Synthesis of cysteinyl lts was assessed in patients with ad and healthy