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Increased levels of plasma brain-derived neurotrophic factor (BDNF) in children with attention deficit-hyperactivity disorder (ADHD)

✍ Scribed by Se-Hoon Shim; Young Hwangbo; Young-Joon Kwon; Hee-Yeon Jeong; Bun-Hee Lee; Heon-Jeong Lee; Yong-Ku Kim

Book ID: 116841396
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 240 KB
Volume: 32
Category: Article
ISSN: 0278-5846
DOI: 10.1016/j.pnpbp.2008.08.005

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## Abstract Several lines of evidence indicate an involvement of brain derived neurotrophic factor (BDNF) in body weight regulation and activity: heterozygous __Bdnf__ knockout mice (__Bdnf__^+/−^) are hyperphagic, obese, and hyperactive; furthermore, central infusion of BDNF leads to severe, dose‐