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Increased interleukin-17 production in patients with systemic sclerosis

✍ Scribed by Kazuhiro Kurasawa; Koichi Hirose; Hideki Sano; Hideharu Endo; Hiroshi Shinkai; Yasushi Nawata; Katsuhiko Takabayashi; Itsuo Iwamoto

Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
939 KB
Volume
43
Category
Article
ISSN
0004-3591

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## Abstract ## Objective To examine the expression and regulation of interleukin‐21 (IL‐21) and IL‐21 receptor (IL‐21R) in patients with systemic sclerosis (SSc; scleroderma). ## Methods Skin biopsy specimens were obtained from 23 patients with SSc and 15 healthy controls. IL‐21/IL‐21R messenger