Increased immunoreactive interleukin-5 levels in blister fluids of bullous pemphigoid
β Scribed by H. Endo; I. Iwamoto; M. Fujita; S. Okamoto; S. Yoshida
- Publisher
- Springer-Verlag
- Year
- 1992
- Tongue
- English
- Weight
- 282 KB
- Volume
- 284
- Category
- Article
- ISSN
- 0340-3696
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## Background: Bullous pemphigoid (bp) often provokes blood and tissue eosinophilia, which suggests that some chemoattractants modulate the eosinophil infiltration in bp. eotaxin, a cc chemokine, strongly attracts eosinophils, and interleukin (il)-5 induces eosinophil differentiation, proliferation
Few and contrasting data are available in the literature concerning the levels of various cytokines in blister fluid (BF) and in the serum of patients affected with bullous pemphigoid (BP). Using commercially available ELISA kits, this study reports the levels of 11 cytokines detected both in BF and