Determination of tumor necrosis factor in blister fluids of bullous pemphigoid
β Scribed by H. Takematsu; H. Ohta; H. Tagami
- Publisher
- Springer-Verlag
- Year
- 1991
- Tongue
- English
- Weight
- 214 KB
- Volume
- 283
- Category
- Article
- ISSN
- 0340-3696
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Bullous pemphigoid (BP) has been suggested to be an autoimmune inflammatory disease affecting the cutaneous basement membrane zone (BMZ) [7]. Immunologic abnormalities include circulating complement-activating autoantibodies against BP antigen [6,12]. Current evidence suggests that the inflammatory
Few and contrasting data are available in the literature concerning the levels of various cytokines in blister fluid (BF) and in the serum of patients affected with bullous pemphigoid (BP). Using commercially available ELISA kits, this study reports the levels of 11 cytokines detected both in BF and