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Increased IgM B cell differentiation lymphokine production by T lymphocytes from patients with primary biliary cirrhosis

✍ Scribed by José Luis Menéndez-Caro; Melchor Alvarez-Mon; José Antonio Girón; Luis Manzano; Aurelio Garrido; Luis Abreu; Agustín Albillos; Alberto Durántez


Book ID
118566380
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
608 KB
Volume
20
Category
Article
ISSN
0168-8278

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Primary biliary cirrhosis (PBC) is a disease that typically affects middle-aged women and is characterized by progressive intrahepatic cholestasis which leads ultimately to cirrhosis, portal hypertension and hepatocellular failure (1). The underlying histopathological lesion in PBC is a chronic, non