INCREASED FREQUENCY OF RECOMBINATION IN HLA REGION IN LEUKAEMIC FAMILIES
β Scribed by Bashir, H; Honeyman, M; Doran, T; Lane, J
- Book ID
- 123132729
- Publisher
- The Lancet
- Year
- 1982
- Tongue
- English
- Weight
- 305 KB
- Volume
- 320
- Category
- Article
- ISSN
- 0140-6736
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π SIMILAR VOLUMES
Progressive systemic sclerosis (scleroderma) is a connective tissue disease of unknown etiology (1). The demonstration of a mononuclear cell infiltrate in the early lesions of scleroderma and the frequent occurrence of serologic abnormalities suggest an immunologic pathogenesis for this disease (1).
A systematic study of 42 Greek DMD~MD families using 14 polymorphic markers that span the dystrophin gene was performed in order to assess the position and frequency of recombinants in the Greek population and to test whether "hot spots" of recombination and deletions coincide when exclusively study