Increased frequency of JC virus type 2 and of dual infection with JC virus type 1 and 2 in Italian progressive multifocal leukoencephalopathy patients
โ Scribed by Pasquale Ferrante; Monica Mediati; Rita Caldarelli-Stefano; Loredana Losciale; Roberta Mancuso; Anna Elisabetta Cagni; Renato Maserati
- Book ID
- 111739039
- Publisher
- Springer US
- Year
- 2001
- Tongue
- English
- Weight
- 132 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1355-0284
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Progressive multifocal leukoencephalopathy (PML), a viral-induced demyelinating disease, is becoming relatively common, while many diagnostic and pathogenetic aspects remain to be clarified. A study was therefore undertaken in 64 AIDS patients suffering from various neurological disorders, including
## Abstract Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system, which is thought to be a result of the reactivation of JC virus (JCV), a human polyomavirus. The disease occurs in individuals with immunosuppression and in recent years there has
## Abstract __JC virus__ (JCV) causes progressive multifocal leukoencephalopathy under conditions of immunosuppression, especially associated with HIV. Despite the high prevalence of HIVโ1 infection, few cases of progressive multifocal leukoencephalopathy have been reported and only a small number