Increased frequency of complement C4B deficiency in rheumatoid arthritis
โ Scribed by William F. C. Rigby; Yee Ling Wu; Moe Zan; Bi Zhou; Sanna Rosengren; Cheryl Carlson; Whitney Hilton; C. Yung Yu
- Book ID
- 112002601
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 132 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0004-3591
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## Abstract Metabolic turnover determined by radioiodide labeled C4 and Factor B was studied in 18 patients with rheumatoid arthritis (RA) and 19 normal control subjects as a means of estimating the relative ratio of consumption of components in the classical and alternative pathways of complement
Forty patients with juvenile rheumatoid arthritis (JRA) were examined for C3b receptor (CRl) levels on erythrocytes (by an enzyme-linked immunosorbent assay), levels of circulating immune complexes (IC) (by a polyethylene glycol precipitation-complement consumption method), C3d split products (by in