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Increased expression ofβ-catenin in brain microvessels of a segmentally trisomic (Ts65Dn) mouse model of Down syndrome

✍ Scribed by Andrzej W. Vorbrodt; Shuyun Li; W. Ted Brown; Narayan Ramakrishna

Book ID
113077077
Publisher
Springer-Verlag
Year
2008
Tongue
English
Weight
532 KB
Volume
36
Category
Article
ISSN
1559-7105

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## Abstract Agonist‐ and guanine‐nucleotide‐stimulated phospholipase C‐β (PLC) activity was characterized in crude plasma membrane preparations from cerebral cortex, hippocampus and cerebellum of Ts65Dn mice, a model for Down syndrome, and their control littermates. The levels of expression of PLC‐