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Increased expression of HSP27 linked to vincristine resistance in human gastric cancer cell line

โœ Scribed by Yi-Xuan Yang; Xue-Feng Sun; Ai-Lan Cheng; Gui-Ying Zhang; Hong Yi; Yi Sun; Huai-Dong Hu; Peng Hu; Feng Ye; Zhu-Chu Chen; Zhi-Qiang Xiao

Publisher
Springer-Verlag
Year
2008
Tongue
English
Weight
474 KB
Volume
135
Category
Article
ISSN
1432-1335

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The role of HSP27 in cell growth and resistance to stress was investigated using murine fibrosarcoma L929 cells (normally devoid of constitutively expressed small HSPs) and human osteoblast-like SaOS-2 cells stably transfected with a human hsp27 expression vector. Our data showed that our L929 cells