## Abstract In amyotrophic lateral sclerosis (ALS), neuronal loss and axonal degeneration occur in motor neurons. Although there is limited axonal regeneration, surviving motor neurons send collateral sprouts to denervated muscle fibers. GAPโ43, a protein enriched in growth cones and synaptic termi
โฆ LIBER โฆ
Increased expression of growth-associated protein 43 on the surface of the anterior horn cells in amyotrophic lateral sclerosis
โ Scribed by A. Ikemoto; Asao Hirano; Ichiro Akiguchi
- Publisher
- Springer-Verlag
- Year
- 1999
- Tongue
- English
- Weight
- 306 KB
- Volume
- 98
- Category
- Article
- ISSN
- 0001-6322
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Amyotrophic lateral sclerosis (ALS) is associated with increased numbers of microglia within the CNS. However, it is unclear to what extent bone marrow (BM)-derived cells contribute to this microgliosis. We have studied the adoptive transfer of green fluorescent protein (GFP)-labeled whole BM cells