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Increased expression of Flt4 (vascular endothelial growth factor receptor-3) in duodenal mucosa of patients with protein-losing enteropathy

✍ Scribed by Kitagawa, Yoshitake; Hokari, Ryota; Katoh, Shingo; Matsuzaki, Koji; Kawaguchi, Atsushi; Nagao, Shigeaki; Iwai, Atsuhiro; Miyahara, Toru; Itoh, Kazuro; Miura, Soichiro; Otani, Akio; Alitalo, Kari

Book ID: 124122905
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 176 KB
Volume: 120
Category: Article
ISSN: 0016-5085
DOI: 10.1016/S0016-5085(08)81410-2

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## Abstract ## BACKGROUND Vascular endothelial growth factor C (VEGF‐C) plays an important role in lymphangiogenesis and activates VEGF receptor 3 (VEGFR‐3). By contrast, lymphatic spread is an important prognostic factor in patients with nonsmall cell lung carcinoma (NSCLC). The objective of the