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Increased DNA methylation status of the serotonin receptor 5HTR1A gene promoter in schizophrenia and bipolar disorder

✍ Scribed by Anthony Carrard; Annick Salzmann; Alain Malafosse; Félicien Karege


Book ID
113667622
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
174 KB
Volume
132
Category
Article
ISSN
0165-0327

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Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter that mediates a wide range of central nervous functions by activating multiple 5-HT receptor subtypes. A possible irregularity of serotonergic neurotransmission has been implicated in a variety of neuropsychiatric diseases. In the present s