There is evidence indicating that density of 5-HT2A receptors is altered in brain regions of depressed suicide victims and in platelets of suicidal subjects with major depression or schizophrenia. Recent studies have also shown an association between the allele C of 102T/C polymorphism in the 5-HT2A
โฆ LIBER โฆ
Genetic association analysis of serotonin 2A receptor gene (HTR2A) with bipolar disorder and major depressive disorder in the Japanese population
โ Scribed by Taro Kishi; Tsuyoshi Kitajima; Tomoko Tsunoka; Masashi Ikeda; Yoshio Yamanouchi; Yoko Kinoshita; Kunihiro Kawashima; Tomo Okochi; Takenori Okumura; Toshiya Inada; Norio Ozaki; Nakao Iwata
- Book ID
- 116776092
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 103 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0168-0102
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## Abstract ## Objective Several investigations have suggested that alterations in serotonin 6 (5โHT6) receptors might be associated with the pathophysiology of major depressive disorder (MDD), and that 5โHT6 receptors might be a therapeutic target for serotonin selective reuptake inhibitor (SSRI)