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Increased cyclooxygenase 2 (COX-2) expression occurs frequently in precursor lesions of human adenocarcinoma of the lung

✍ Scribed by Hosomi, Yukio; Yokose, Tomoyuki; Hirose, Yuko; Nakajima, Ryu; Nagai, Kanji; Nishiwaki, Yutaka; Ochiai, Atsushi

Book ID
118569427
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
354 KB
Volume
30
Category
Article
ISSN
0169-5002

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Increasing cyclooxygenase-2 (cox-2) gene
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## Abstract Previous studies from our laboratory and others have suggested that increased expression of __cox‐2__ is important in the genesis of esophageal adenocarcinoma. __In vitro__ studies suggest that __cox‐2__ regulates expression of the anti‐apoptotic protein bcl‐2, thus possibly accounting