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Increased concentrations of liver cholesterol in rats fed lactulose (Short communication)

✍ Scribed by Beynen, A. C.

Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
113 KB
Volume
33
Category
Article
ISSN
0027-769X

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✦ Synopsis

The disaccharide lactulosc (/?-D-galactopyranosyl-( l-4)-D-fructofuranose) is thought to be poorly hydrol i d by intestinal enzymes but is broken down by microorganisms in the colon. Thus lactulose shares with pectin similar characteristics [I]. Lactulose is used in the food industry and in the treatment of constipation.

There is preliminary evidence that dietary lactulose (5%, w/w) causes increased conantrations of serum and h e r cholesterol in rats when compared with pectin [2]. This paper describes dose-response relatioriships between dietary lactulose and cholesterol in either serum or liver.

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