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Increased CD39 expression on CD4+T lymphocytes has clinical and prognostic significance in chronic lymphocytic leukemia

โœ Scribed by Perry, Chava; Hazan-Halevy, Inbal; Kay, Sigi; Cipok, Michal; Grisaru, Dan; Deutsch, Varda; Polliack, Aaron; Naparstek, Elizabeth; Herishanu, Yair

Book ID
113027948
Publisher
Springer
Year
2012
Tongue
English
Weight
362 KB
Volume
91
Category
Article
ISSN
0939-5555

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Soluble CD83 (sCD83), a potent immunosuppressive agent, circulates at elevated levels in some chronic lymphocytic leukemia (CLL) patients. We report that CLL patients with elevated plasma sCD83 levels had significantly shorter (P=0.038) treatment free survival. Culture of CLL cells with solid phase