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Increased affinity of platelet dopamine-binding to D 2 -receptors in migraineurs: implications of the dopaminergic system in migraine

✍ Scribed by Akerman, Simon

Book ID
120451900
Publisher
Future Medicine
Year
2009
Tongue
English
Weight
155 KB
Volume
4
Category
Article
ISSN
1479-6708

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## Abstract In this study we examined the selectivity of dopamine (DA) for rat striatal DA D~1~ and D~2~ receptors. In a Krebs‐HEPES buffer, the K~i~ values of DA for D~1~ binding sites (labelled with [^3^H]SCH23390) and D~2~ binding sites (labelled with [^3^H]spiroperidol) in striatal membranes am