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Increased 3-Hydroxykynurenine serum concentrations differentiate Alzheimer’s disease patients from controls

✍ Scribed by Markus J. Schwarz, Gilles J. Guillemin…

Book ID
120895005
Publisher
Springer-Verlag
Year
2012
Tongue
English
Weight
276 KB
Volume
263
Category
Article
ISSN
1433-8491

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## Abstract To investigate the possible role of oxidative RNA damage in the pathogenesis of Alzheimer's disease (AD), the concentrations of the oxidative stress marker 8‐hydroxyguanosine (8‐OHG) were measured in the cerebrospinal fluid (CSF) and the serum of patients with AD and control subjects. T