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Increase of Fas-induced apoptosis by inhibition of extracellular phosphorylation of Fas receptor in Jurkat cell line

โœ Scribed by C. Lautrette*; E. Loum-Ribot; D. Petit; C. Vermot-Desroches; J. Wijdenes; M. O. Jauberteau


Publisher
Springer
Year
2006
Tongue
English
Weight
398 KB
Volume
11
Category
Article
ISSN
1360-8185

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Background and Objectives: Fas (APO-1) induces apoptosis after binding Fas ligand (FasL). Evidence suggests that tumors may use this interaction to evade the host immune response. Fas/FasL expression has not been reported in esophageal cancer. We hypothesized that Fas expression would render esophag