Inhibition of Fas-mediated apoptosis by the B cell antigen receptor through c-FLIP

Negative regulation of antigen receptor-

Negative regulation of antigen receptor-mediated signaling by constitutive asociation of CD5 with the SHP-1 protein tyrosine phosphatase in B-1 B cells

✍ Goutam Sen; Gabriel Bikah; Chandrasekar Venkataraman; Subbarao Bondada 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 172 KB 👁 2 views

CD5, a membrane-associated glycoprotein, has been shown to negatively regulate antigen receptor-mediated growth responses in peritoneal B lymphocytes, thymocytes and mature T cells. The CD5-expressing peritoneal B cells (B-1) that are normally unresponsive to B cell receptor (BCR)-mediated growth si