✦ LIBER ✦

Increase in concanavalin a binding sites in mouse blastocysts during implantation

✍ Scribed by Wu, J. T. ;Chang, M. C.

Book ID: 102337101
Publisher: John Wiley and Sons
Year: 1978
Tongue: English
Weight: 286 KB
Volume: 205
Category: Article
ISSN: 0022-104X
DOI: 10.1002/jez.1402050314

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✦ Synopsis

Abstract

The number of concanavalin A (Con A) binding sites were determined in mouse blastocysts before and during implantation. In intact pregnant mice (Day 1 = day of finding vaginal plug), the Con A binding sites per blastocyst were increased from 169 million on Day 4 morning to 1160 million on Day 5 morning when implantation was under way. In pregnant mice ovariectomized on Day 3 and treated daily with 1 mg progesterone, the Con A binding sites per blastocyst on Day 9 (inactive) were 363 million; if the mice had received an additional injection of estradiol 24 hours earlier to induce implantation, the Con A binding sites were increased to 1211 millions. Thus, a more than twofold increase in the Con A binding sites occurs in the mouse blastocyst during implantation.

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