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Incorporation of Tellurocysteine into Glutathione Transferase Generates High Glutathione Peroxidase Efficiency

✍ Scribed by Xiaoman Liu; Louis A. Silks; Cuiping Liu; Morgane Ollivault-Shiflett; Xin Huang; Jing Li; Guimin Luo; Ya-Ming Hou; Junqiu Liu; Jiacong Shen

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
389 KB
Volume
121
Category
Article
ISSN
0044-8249

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Incorporation of Tellurocysteine into Gl
Incorporation of Tellurocysteine into Glutathione Transferase Generates High Glutathione Peroxidase Efficiency
✍ Xiaoman Liu; Louis A. Silks; Cuiping Liu; Morgane Ollivault-Shiflett; Xin Huang; 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 389 KB

## Abstract **A rival to native peroxidase!** An existing binding site for glutathione was combined with the catalytic residue tellurocysteine by using an auxotrophic expression system to create an engineered enzyme that functions as a glutathione peroxidase from the scaffold of a glutathione trans