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Incorporation of phencyclidine and its hydroxylated metabolites into hair

✍ Scribed by Tomoaki Sakamoto; Akira Tanaka; Yuji Nakahara

Book ID
117175387
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
669 KB
Volume
62
Category
Article
ISSN
0024-3205

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## Abstract This paper describes the synthesis of deuterium‐labelled paclitaxel and its hydroxyl metabolite. Paclitaxel labelled with ^2^H was obtained in four steps using the commercially available [^2^H~5~]benzoic chloride as the stable labelled reagent with a 40% overall yield. The hydroxyl meta