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Incorporation of 5-fluorouracil into rat liver tumor and normal tissues and the liver nucleotide profile after administration by the hepatic artery during portal venous branch ligation

✍ Scribed by B. Jakobsson; G. Roos; I. A. ElHag; P. -E. Jönsson; U. Stenram


Book ID
110562480
Publisher
Springer
Year
1992
Tongue
English
Weight
487 KB
Volume
192
Category
Article
ISSN
0372-8722

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The cytotoxicity of 5-FUra has been related to its incorporation into RNA. In a model of secondary liver cancer in the rat, the incorporation of 5-FUra into the acid-soluble fraction, RNA and DNA of several normal tissues and an adenocarcinoma of the colon transplanted to the liver was determined. A