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The incorporation of 5-fluorouracil into rat liver tumor and normal tissues after administration by the hepatic artery during temporary portal vein clamping

✍ Scribed by I. A. El Hag; B. Jakobsson; P. -E. Jönsson; U. Stenram

Publisher
Springer
Year
1990
Tongue
English
Weight
506 KB
Volume
190
Category
Article
ISSN
0372-8722

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The cytotoxicity of 5-FUra has been related to its incorporation into RNA. In a model of secondary liver cancer in the rat, the incorporation of 5-FUra into the acid-soluble fraction, RNA and DNA of several normal tissues and an adenocarcinoma of the colon transplanted to the liver was determined. A