✦ LIBER ✦

Inclusion complexation of doxorubicin and daunorubicin with cyclodextrins

✍ Scribed by O. Bekers; J.H. Beijnen; M. Otagiri; A. Bult; W.J.M. Underberg

Publisher: Elsevier Science
Year: 1990
Tongue: English
Weight: 225 KB
Volume: 8
Category: Article
ISSN: 0731-7085
DOI: 10.1016/0731-7085(90)80100-4

No coin nor oath required. For personal study only.

✦ Synopsis

The interaction of alpha-, beta- and gamma-cyclodextrins with the anthracycline antibiotics doxorubicin and daunorubicin was investigated by LC, circular dichroism (CD) and absorption spectroscopy. All studies were performed in aqueous media at different temperatures and pH values. The anthracyclines complex only with gamma-cyclodextrin. Lineweaver-Burk and Scott's plots were used to calculate the stability constants of the anthracycline-gamma-cyclodextrin inclusion complexes.

📜 SIMILAR VOLUMES

Inclusion complex of fenbufen with β-cyc

Inclusion complex of fenbufen with β-cyclodextrin

✍ I. Bratu; J. M. Gavira-Vallejo; A. Hernanz; M. Bogdan; Gh. Bora 📂 Article 📅 2004 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 108 KB 👁 1 views

## Abstract An inclusion complex of fenbufen with β‐cyclodextrin (β‐CD) in aqueous solution was characterized by ^1^H‐NMR spectroscopy. The [1:1] stoichiometry was determined and a stability constant of several 1000s (__M__^−1^) was calculated. The geometry of the inclusion complex was established

Photostability Study of Doxorubicin Aque

Photostability Study of Doxorubicin Aqueous Solution Enhanced by Inclusion Interaction between Doxorubicin and Hydroxypropyl-β-cyclodextrin

✍ Mingli Peng; Yanhong Liu; Hua Zhang; Yali Cui; Gaohong Zhai; Chao Chen 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 172 KB

Electrochemistry of inclusion complexes

Electrochemistry of inclusion complexes of organometallics: Complexation of ferrocene and azaferrocene by cyclodextrins

✍ V.V. Strelets; I.A. Mamedjarova; M.N. Nefedova; N.I. Pysnograeva; V.I. Sokolov; 📂 Article 📅 1991 🏛 Elsevier Science ⚖ 466 KB

Synthesis of novel modified p-cyclodextr

Synthesis of novel modified p-cyclodextrins and their fluorescence studies of inclusion complexation with Rhodamine B

✍ Jin Lan; Liu Yu 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 163 KB

Thermochemical study of cyclodextrin inc

Thermochemical study of cyclodextrin inclusion complexes

✍ E. Siimer; M. Kõbu; M. Kurvits 📂 Article 📅 1990 🏛 Elsevier Science 🌐 English ⚖ 422 KB

Cyclomaltoheptaose (β-cyclodextrin) and

Cyclomaltoheptaose (β-cyclodextrin) and hydroxyethyl-substituted β-cyclodextrin inclusion complex formation with chlorogenic acid: solvent effects on inclusion complex stability

✍ Peter L. Irwin; Janine N. Brouillette; Kevin B. Hicks 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 795 KB

The inclusion complexes of cyclomaltoheptaose (/3-CD) and /~-CD's 50% hydroxyethyl-substituted derivative (HE-/3-CD) with chlorogenic acid (CA) were studied with regard to temperature and water activity (all2 o = mole fraction = XH2 o = 0.8--0.99; 0.1 M Na phosphate buffer) utilizing first-derivativ