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Inactivation of the Integrin-Linked Kinase (ILK) in osteoblasts increases mineralization

✍ Scribed by El-Hoss, Jad; Arabian, Alice; Dedhar, Shoukat; St-Arnaud, René

Book ID
122154210
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
908 KB
Volume
533
Category
Article
ISSN
0378-1119

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## Abstract Bone resorption requires the adhesion of osteoclasts to extracellular matrix (ECM) components, a process mediated by the α~v~β~3~ integrin. Following engagement with the ECM, integrin receptors signal via multiple downstream effectors, including the integrin‐linked kinase (ILK). In orde