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Inactivation of the Inducible Nitric Oxide Synthase by Peroxynitrite

✍ Scribed by Hühmer, Andreas F. R.; Nishida, Clinton R.; Ortiz de Montellano, Paul R.; Schöneich, Christian


Book ID
126146640
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
323 KB
Volume
10
Category
Article
ISSN
0893-228X

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✍ Jean E. Merrill; Sean P. Murphy; Branislava Mitrovic; Allan Mackenzie-Graham; Jo 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 563 KB

It has been previously demonstrated that microglia and astrocytes produce micromolar amounts of nitric oxide in vitro. In this study, we demonstrate that primary rat oligodendrocytes can be stimulated to produce iNOS mRNA as detected by Northern blot and in situ hybridization analysis and a 131-kDa