Inactivation of Non-A, Non-B Virus Infectivity by a Beta Propiolactone/Ultraviolet Irradiation Treatment and Aerosil Adsorption Procedure Used for Preparation of a Stabilized Human Serum

Inactivation of the hutchinson strain of

Inactivation of the hutchinson strain of non-A, non-B hepatitis virus by combined use of β-propiolactone and ultraviolet irradiation

✍ Dr. Alfred M. Prince; Wolfgang Stephan; Herbert Dichtelmüller; Betsy Brotman; Te 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 English ⚖ 857 KB

A beta-propiolactone/ultraviolet irradiation procedure (beta PL/UV) has been evaluated for its ability to inactivate 30,000 chimpanzee infectious doses of the Hutchinson strain of non-A, non-B (NANB) virus. The chimpanzees were inoculated with plasma to which this dose of the titrated virus had been