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Inactivation of mammalian brain glutamine synthetase by oxygen radicals

✍ Scribed by Nina Felice Schor

Book ID
115798149
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
416 KB
Volume
456
Category
Article
ISSN
0006-8993

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Inactivation of glutamine synthetase by
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✍ C. Peter Heinrich; Helmut Holzer πŸ“‚ Article πŸ“… 1970 πŸ› Springer 🌐 English βš– 385 KB

The glutamine synthetase was inactivated in vivo by incubation of the cell suspension with 2 β€’ 10 -a ~ NH~ + for 2 min. The inactivated glutamine synthetase was extracted from the cells and purified 20-fold. Incubation of the purified glutamine synthetase with phosphodiesterase regenerated the bios