✦ LIBER ✦

Inactivation of Inosine 5‘-Monophosphate Dehydrogenase by the Antiviral Agent 5-Ethynyl-1-β- d -Ribofuranosylimidazole-4-Carboxamide 5‘-Monophosphate †

✍ Scribed by Wang, Wen; Papov, Vladimir V.; Minakawa, Noriaki; Matsuda, Akira; Biemann, Klaus; Hedstrom, Lizbeth

Book ID: 127146818
Publisher: American Chemical Society
Year: 1996
Tongue: English
Weight: 811 KB
Volume: 35
Category: Article
ISSN: 0006-2960
DOI: 10.1021/bi951499q

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

ChemInform Abstract: Mechanism-based Des

ChemInform Abstract: Mechanism-based Design of Inosine 5′-Monophosphate Dehydrogenase Inhibitors: Synthesis and Biological Activities of 5-Ethynyl-1-β-D-ribofuranosylimidazole-4-carboxamide (EICAR) and Its Derivatives

✍ Noriaki Minakawa; Akira Matsuda 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 29 KB 👁 1 views

Synthesis of a Methylene Analog of 5-Ami

Synthesis of a Methylene Analog of 5-Amino-1-β- D -ribofuranosylimidazole-4-carboxamide Monophosphate (ZMP)

✍ KOHYAMA, Naoki; HAYASHI, Tatsuya; YAMAMOTO, Yukio 📂 Article 📅 2005 🏛 Japan Science and Technology Information Aggregato 🌐 English ⚖ 75 KB

Synthesis of 5-fluoro-1-β-D-ribofuranosy

Synthesis of 5-fluoro-1-β-D-ribofuranosylimidazole-4-carboxamide, an antiviral agent and inhibitor of polynucleotide biosynthesis

✍ John C. Reepmeyer; Kenneth L. Kirk; Louis A. Cohen 📂 Article 📅 1975 🏛 Elsevier Science 🌐 French ⚖ 214 KB

Recognition of the biomedical potential of ring-fluorinated analogs of natural imidazoles has provided the stimulus for concentrated synthetic efforts in this laboratory. Our discovery

Differential anti-hepatitis B virus acti

Differential anti-hepatitis B virus activity in vitro of three potent of inosine monophosphate dehydrogenase inhibitors: mycophenolic acid (MPA), 5-ethynyl-1-β-d-ribofuranosyli-midazole-4-carboxamide (EICAR) and ribavirin

✍ Z.J. Gong; S. De Meyer; C. Clarysse; J.F. van Pelt; T. Coopmans; J. Neyts; E. De 📂 Article 📅 1998 🏛 Elsevier Science 🌐 English ⚖ 171 KB

Selective Inhibition of Human Molt-4 Leu

Selective Inhibition of Human Molt-4 Leukemia Type II Inosine 5‘-Monophosphate Dehydrogenase by the 1,5-Diazabicyclo[3.1.0]hexane-2,4-diones †

✍ Barnes, Betsy J.; Eakin, Ann E.; Izydore, Robert A.; Hall, Iris H. 📂 Article 📅 2000 🏛 American Chemical Society 🌐 English ⚖ 287 KB

1-β-D-Ribofuranosyl-1,2,4-triazole-3-car

1-β-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide (ribavirin) and 5-ethynyl-1-β-D-ribofuranosylimidazole-4-carboxamide (EICAR) markedly potentiate the inhibitory effect of 2′,3′-dideoxyinosine on human immunodeficiency virus in peripheral blood lymphocytes

✍ Jan Balzarini; Chong-Kyo Lee; Dominique Schols; Erik De Clercq 📂 Article 📅 1991 🏛 Elsevier Science 🌐 English ⚖ 368 KB