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Inactivation of Caspase-1 in Rodent Brain: A Novel Anticonvulsive Strategy

✍ Scribed by Teresa Ravizza; Sian-Marie Lucas; Silvia Balosso; Liliana Bernardino; George Ku; Francesco Noé; Joao Malva; John C. R. Randle; Stuart Allan; Annamaria Vezzani


Book ID
109108965
Publisher
Wiley (Blackwell Publishing)
Year
2006
Tongue
English
Weight
290 KB
Volume
47
Category
Article
ISSN
0013-9580

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✍ David C. Piper; B. S. Meldrum; C. R. Gardner 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 English ⚖ 283 KB 👁 1 views

## Abstract RU 31124, a new anticonvulsant 1,4‐benzodiazepine was compared with clonazepam in a series of tests in rats and mice. It demonstrated greater anticonvulsant potency whilst having equivalent sedative properties to clonazepam. This profile of activity was confirmed in the photosensitive b